Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156559 | 0.92 | KDM4E (0.32) | POLBGLANPSR1KDM4EALDH1A1 | |
| SCHEMBL13156629 | 0.89 | FFAR1 (0.34) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL15150406 | 0.87 | MEN1 (0.32) | GLANPSR1OGA | |
| SCHEMBL15150405 | 0.85 | IDO1 (0.32) | GLANPSR1OGA | |
| SCHEMBL12554702 | 0.85 | IDO1 (0.31) | GLANPSR1 | |
| SCHEMBL13156670 | 0.80 | RAB9A (0.32) | NPC1POLBRAB9ASMN1; SMN2LDHA | |
| SCHEMBL12553285 | 0.76 | — | — | |
| SCHEMBL13156549 | 0.75 | ALDH1A1 (0.31) | KDM4EALDH1A1 | |
| SCHEMBL12554719 | 0.74 | ANO1 (0.30) | — | |
| SCHEMBL12771856 | 0.74 | CYP3A4 (0.33) | NPC1POLBRAB9AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799827-B2 | Macrocyclic compounds useful as pharmaceuticals | EISAI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |