Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156670 | 0.91 | RAB9A (0.32) | RAB9ANPC1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL13156557 | 0.89 | FFAR1 (0.33) | FFAR1RAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL13156683 | 0.81 | CYP3A4 (0.32) | — | |
| SCHEMBL13156559 | 0.80 | KDM4E (0.32) | POLBALDH1A1GLANPSR1 | |
| SCHEMBL13903894 | 0.80 | CYP3A4 (0.34) | FFAR1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13904105 | 0.80 | CYP3A4 (0.34) | FFAR1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13904063 | 0.79 | OGA (0.31) | — | |
| SCHEMBL12772104 | 0.77 | APLNR (0.33) | — | |
| SCHEMBL13904060 | 0.77 | APLNR (0.33) | — | |
| SCHEMBL13156646 | 0.75 | MAPT (0.32) | RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799827-B2 | Macrocyclic compounds useful as pharmaceuticals | EISAI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |