Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156557 | 0.92 | FFAR1 (0.33) | KDM4EALDH1A1GLANPSR1OGA | |
| SCHEMBL13156670 | 0.89 | RAB9A (0.32) | KDM4EALDH1A1LMNAMAPTHPGD | |
| SCHEMBL15150406 | 0.86 | MEN1 (0.32) | GLANPSR1OGA | |
| SCHEMBL15150405 | 0.85 | IDO1 (0.32) | GLANPSR1OGA | |
| SCHEMBL12554702 | 0.84 | IDO1 (0.31) | GLANPSR1 | |
| SCHEMBL13156629 | 0.80 | FFAR1 (0.34) | ALDH1A1GLANPSR1POLB | |
| SCHEMBL12553285 | 0.74 | — | — | |
| SCHEMBL13156549 | 0.73 | ALDH1A1 (0.31) | KDM4EALDH1A1MAPT | |
| SCHEMBL17733174 | 0.72 | CYP3A4 (0.36) | KDM4EALDH1A1MAPTHPGDGLA | |
| SCHEMBL15580593 | 0.72 | CYP3A4 (0.36) | KDM4EALDH1A1MAPTHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799827-B2 | Macrocyclic compounds useful as pharmaceuticals | EISAI CO., LTD. (JP) | 2010-09-21 | — | — | US | disclosed |