SCHEMBL1315657

SCHEMBL1315657

CCN(C(=O)OC(C)(C)C)c1ccccc1-c1ccc(C(=O)OC)c([N+](=O)[O-])c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CSNK2A1 P68400 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
ALDH1A1 P00352 4/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1317223 0.87 ABCB1 (0.38) ABCB1MEN1KMT2AKDM4ESLC6A2
SCHEMBL27989358 0.85 ALDH1A1 (0.35) MEN1KMT2ASMN1; SMN2ALDH1A1NPSR1
SCHEMBL1315548 0.85 ABCB1 (0.37) ABCB1MEN1KMT2AKDM4ESLC6A2
SCHEMBL1316617 0.84 ALDH1A1 (0.40) MEN1KMT2AKDM4ESLC6A2SLC6A4
SCHEMBL1315457 0.83 SLC6A3 (0.41) ABCB1MEN1KMT2AKDM4ESLC6A2
SCHEMBL1316834 0.81 BRD4 (0.37) ABCB1MEN1KMT2AKDM4EALDH1A1
SCHEMBL27828368 0.80 MAPT (0.44) MEN1KMT2ASMN1; SMN2ALDH1A1NPSR1
SCHEMBL1317398 0.77 ALDH1A1 (0.37) ABCB1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL1315221 0.77 TRPV1 (0.42) ABCB1MEN1KMT2AKDM4ESLC6A2
SCHEMBL12121441 0.77 ALDH1A1 (0.39) ABCB1MEN1KMT2AKDM4ESLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 ABCB1 4395/4885MEN1 3020/4885KMT2A 950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.