Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12117129 | 0.89 | ALDH1A1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12117002 | 0.82 | MAPT (0.40) | MAPTALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL17005447 | 0.77 | GAA (0.48) | MAPTALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL1316185 | 0.75 | SMN1; SMN2 (0.48) | MAPTALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL28802244 | 0.74 | ALDH1A1 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25257607 | 0.74 | MAPT (0.48) | MAPTALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL16330862 | 0.72 | GAA (0.43) | CA12CA1CA2CA9MAPT | |
| SCHEMBL13832650 | 0.71 | GAA (0.66) | MAPTALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL12117003 | 0.70 | PIK3CA (0.39) | — | |
| SCHEMBL30630683 | 0.70 | MAPT (0.40) | MAPTALDH1A1KDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES INC (US) | 2015-09-17 | — | — | US | disclosed |
| US-9045440-B2 | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045440-B2 | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| US-9045440-B2 | Desazadesferrothiocin and desazadesferrothiocin polyether analogues as metal chelation agents | FERROKIN BIOSCIENCES, INC. (US) | 2015-06-02 | — | — | US | disclosed |
| EP-2566854-A2 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | Shire LLC (US) | 2013-03-13 | — | — | EP | disclosed |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FerroKin BioScience, Inc. (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FerroKin BioScience, Inc. (US) | 2013-02-28 | — | — | US | disclosed |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FerroKin BioScience, Inc. (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2011140232-A2 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2011140232-A2 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC (US) | 2011-11-10 | — | — | WO | disclosed |
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | FERROKIN BIOSCIENCES, INC. (US) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275636-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, FTH1 | CA12 1737/4885CA1 2683/4885CA2 2273/4885 |
| US-20130053387-A1 | DESAZADESFERROTHIOCIN AND DESAZADESFERROTHIOCIN POLYETHER ANALOGUES AS METAL CHELATION AGENTS | SLC39A14, SLC40A1, FTH1 | CA12 1737/4885CA1 2683/4885CA2 2273/4885 |
| US-20150259306-A1 | DESAZADESFERROTHIOCIN ANALOGUES AS METAL CHELATION AGENTS | SLC40A1, SLC39A14, HAMP | CA12 1880/4885CA1 2847/4885CA2 2168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.