SCHEMBL13158271

SCHEMBL13158271

O=C1CCCN1S(=O)(=O)C(S(=O)(=O)N1CCCC1=O)S(=O)(=O)N1CCCC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
BRD4 O60885 1/20 0.39
BRD2 P25440 1/20 0.39
PIK3CD O00329 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
RCE1 Q9Y256 1/20 0.34
LMNA P02545 3/20 0.33
TP53 P04637 2/20 0.33
CYP2C19 P33261 1/20 0.33
AKR1C3 P42330 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14022334 0.90 GAA (0.39) GAABRD4BRD2PIK3CDMEN1
SCHEMBL28339322 0.78 GAA (0.48) GAABRD4BRD2PIK3CDMEN1
SCHEMBL10122963 0.76 GAA (0.47) GAABRD4BRD2PIK3CDMEN1
SCHEMBL27210198 0.74 GAA (0.46) GAABRD4BRD2MEN1KMT2A
SCHEMBL14635436 0.74 GAA (0.50) GAABRD4BRD2PIK3CDMEN1
SCHEMBL3779668 0.74 GAA (0.46) GAABRD4BRD2PIK3CDMEN1
SCHEMBL13158265 0.73 GAA (0.44) GAABRD4BRD2PIK3CDMEN1
SCHEMBL29235813 0.73 GAA (0.44) GAABRD4BRD2PIK3CDMEN1
SCHEMBL29905661 0.71 POLB (0.46) GAABRD4BRD2MEN1KMT2A
SCHEMBL10880049 0.70 GAA (0.36) GAABRD4BRD2PIK3CDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249461-A1 TRIARYLAMINE DERIVATIVE MASAKI TOMOHITO 2010-09-30 US disclosed
US-7759504-B2 Diimmonium compound having perchlorate ion or hexafluorophosphate ion as counter ion with sufficient heat resistance and solubility; photopolymerization initiator and electrophotographic photoreceptor FUJIFILM CORPORATION (JP) 2010-07-20 US disclosed
US-20080255387-A1 TRIARYLAMINE DERIVATIVE FUJIFILM CORPORATION (JP) 2008-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249461-A1 TRIARYLAMINE DERIVATIVE ADRB3, YWHAZ, DRD2 GAA 3759/4885BRD4 351/4885BRD2 618/4885
US-20080255387-A1 TRIARYLAMINE DERIVATIVE METTL14, MYH14, TOMM22 GAA 3574/4885BRD4 863/4885BRD2 1532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.