Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8622785 | 0.97 | PABPC1 (0.41) | PABPC1APOBEC3AEIF4HAPOBEC3GCYP2D6 | |
| SCHEMBL1316266 | 0.91 | MEN1 (0.48) | CYP2D6MAPTCYP2C9MEN1TP53 | |
| Iodide SCHEMBL5014654 | 0.90 | HTT (0.50) | CYP2D6MAPTCYP2C9MEN1TP53 | |
| Bromide SCHEMBL8598361 | 0.90 | MEN1 (0.47) | CYP2D6MAPTCYP2C9MEN1TP53 | |
| SCHEMBL14364681 | 0.81 | SMN1; SMN2 (0.50) | CYP2D6MAPTCYP2C9MEN1CYP1A2 | |
| SCHEMBL18588440 | 0.80 | MAPT (0.56) | PABPC1APOBEC3AEIF4HAPOBEC3GCYP2D6 | |
| SCHEMBL19892478 | 0.80 | MAPT (0.52) | PABPC1APOBEC3AEIF4HAPOBEC3GCYP2D6 | |
| Hydrochloric Acid SCHEMBL9618165 | 0.78 | CHKA (0.42) | CYP2D6MAPTCYP2C9MEN1TP53 | |
| SCHEMBL23373037 | 0.78 | MAPT (0.59) | PABPC1APOBEC3AEIF4HAPOBEC3GCYP2D6 | |
| Hydrochloric Acid SCHEMBL1973961 | 0.77 | MEN1 (0.48) | MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771642-B2 | Active particles for bio-analytical applications and methods for their preparation | Alma Mater Studiorum—Universita' di Bologna (IT) | 2014-07-08 | — | — | US | disclosed |
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2011-11-10 | — | — | US | disclosed |
| EP-2328620-A2 | ACTIVE PARTICLES FOR BIO-ANALYTICAL APPLICATIONS AND METHODS FOR THEIR PREPARATION | Alma Mater Studiorum - Università di Bologna (IT) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010013136-A2 | ACTIVE PARTICLES FOR BIO-ANALYTICAL APPLICATIONS AND METHODS FOR THEIR PREPARATION | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | PHOSPHO1, LIPA, ALG1 | PABPC1 676/4885APOBEC3A 4479/4885EIF4H 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.