Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 11/20 | 0.32 |
| ▸ | CHKA | P35790 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 11/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8959775 | 0.88 | CHKA (0.58) | CHKAATMHTTNPC1LMNA | |
| SCHEMBL1316266 | 0.82 | MEN1 (0.48) | CHKABCHEACHEMEN1TP53 | |
| Hydrochloric Acid SCHEMBL9673984 | 0.82 | CHRM2 (0.47) | CHKAMEN1TP53CYP1A2CYP2D6 | |
| Iodide SCHEMBL5014654 | 0.80 | HTT (0.50) | CHKABCHEACHEMEN1TP53 | |
| Bromide SCHEMBL8598361 | 0.80 | MEN1 (0.47) | CHKABCHEACHEMEN1TP53 | |
| Hydrochloric Acid SCHEMBL8959759 | 0.78 | CHKA (0.33) | CHKAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1973961 | 0.78 | MEN1 (0.48) | BCHEACHEMEN1MAPTKMT2A | |
| SCHEMBL1316129 | 0.78 | PABPC1 (0.43) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL8960041 | 0.77 | CHRM2 (0.46) | CHKAACHEMEN1TP53CYP1A2 | |
| SCHEMBL10332332 | 0.76 | BCHE (0.50) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4288090-A | — | — | None | — | — | JP | disclosed |
| JP-H04288090-A | ALKOXYSILYL GROUP-CONTAINING PYRIDINIUM SALT, ITS PRODUCTION AND INTERPHASE TRANSFER CATALYST MADE OF SAME | HUELS AG | 1992-10-13 | — | — | JP | disclosed |