Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 11/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 11/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 2/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 2/20 | 0.35 |
| ▸ | CHKA | P35790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1316266 | 0.98 | MEN1 (0.48) | HTTKDM4ENPC1LMNARAB9A | |
| Bromide SCHEMBL8598361 | 0.96 | MEN1 (0.47) | HTTKDM4ENPC1LMNARAB9A | |
| SCHEMBL1316129 | 0.90 | PABPC1 (0.43) | HTTKDM4ENPC1LMNARAB9A | |
| Bromide SCHEMBL8622785 | 0.87 | PABPC1 (0.41) | HTTKDM4ENPC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL9618165 | 0.80 | CHKA (0.42) | HTTKDM4ENPC1LMNARAB9A | |
| SCHEMBL10332332 | 0.80 | BCHE (0.50) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL8959775 | 0.79 | CHKA (0.58) | HTTNPC1LMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1973961 | 0.78 | MEN1 (0.48) | SMN1; SMN2MEN1MAPTKMT2ABCHE | |
| SCHEMBL14364681 | 0.74 | SMN1; SMN2 (0.50) | KDM4ENPC1LMNARAB9ASMN1; SMN2 | |
| Bromide SCHEMBL7743409 | 0.74 | MEN1 (0.41) | HTTKDM4ENPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247680-B2 | Light energy conversion material | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2012-08-21 | — | — | US | disclosed |
| US-20080057420-A1 | Silica porous material including an electron donor in skeleton; and an electron acceptor; efficiency, durability | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2008-03-06 | — | — | US | disclosed |