Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726413 | 0.82 | CRHBP (0.43) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL31107072 | 0.81 | CRHBP (0.56) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL2033903 | 0.81 | CRHBP (0.56) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL13510717 | 0.79 | ENPP1 (0.40) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL76969 | 0.78 | L3MBTL1 (0.56) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL18996708 | 0.77 | CRHBP (0.44) | CRHBPCRHR2KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL13251224 | 0.76 | ACACA (0.34) | ALDH1A1HPGDHSD17B10MAPTKDM4E | |
| SCHEMBL13251145 | 0.76 | KDM4E (0.33) | ALDH1A1HPGDMAPK1HSD17B10MAPT | |
| SCHEMBL13995119 | 0.76 | GPR84 (0.38) | ALDH1A1HPGDMAPK1HSD17B10MAPT | |
| SCHEMBL13957009 | 0.76 | ENPP1 (0.36) | ALDH1A1MAPTENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100244677-A1 | OLED DEVICE CONTAINING A SILYL-FLUORANTHENE DERIVATIVE | GLOBAL OLED TECHNOLOGY LLC | 2010-09-30 | — | — | US | disclosed |