SCHEMBL13162412

SCHEMBL13162412

Cc1ccccc1C(=O)NCCc1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 4/20 0.82
▸ HPGD P15428 3/20 0.82
▸ POLB P06746 2/20 0.74
▸ ALDH1A1 P00352 1/20 0.74
▸ ALOX12 P18054 1/20 0.74
▸ RAB9A P51151 7/20 0.67
▸ NPC1 O15118 6/20 0.67
▸ MEN1 O00255 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ RECQL P46063 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ CNR1 P21554 1/20 0.58
▸ CNR2 P34972 1/20 0.58
▸ LMNA P02545 1/20 0.57
▸ MAPT P10636 1/20 0.57
▸ PTGS2 P35354 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2228229 0.89 HPGD (0.67) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL14818759 0.88 MAPK1 (0.74) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL14688250 0.86 HPGD (0.63) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL11707705 0.85 HPGD (0.62) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL19579563 0.84 SMN1; SMN2 (0.67) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL13161962 0.84 SMN1; SMN2 (0.60) SMN1; SMN2HPGDPOLBALDH1A1ALOX12
SCHEMBL28574459 0.83 ALDH1A1 (0.73) SMN1; SMN2HPGDPOLBALDH1A1MEN1
SCHEMBL1849467 0.83 MAPT (0.79) SMN1; SMN2HPGDALDH1A1RAB9ANPC1
SCHEMBL1032002 0.83 MAPK1 (0.77) SMN1; SMN2HPGDALDH1A1MEN1KMT2A
SCHEMBL29046318 0.83 SMN1; SMN2 (0.58) SMN1; SMN2HPGDPOLBALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2026-01-27 — — US disclosed
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2024-05-30 — — US disclosed
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-23 — — US disclosed
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections THE TRUSTEES OF INDIANA UNIVERSITY (US) 2023-04-18 — — US disclosed
EP-4135698-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS The Trustees of Indiana University (US) 2023-02-22 — — EP disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 — — US disclosed
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2023-02-16 — — US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 — — US disclosed
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY 2022-05-12 — — US disclosed
WO-2021212010-A2 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS THE TRUSTEES OF INDIANA UNIVERSITY (US) 2021-10-21 — — WO disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 — — US disclosed
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 — — US disclosed
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF ASTELLAS PHARMA INC. (JP) 2010-09-30 — — US disclosed
EP-2206707-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF Astellas Pharma Inc. (JP) 2010-07-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047626-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI SMN1; SMN2 4022/4885HPGD 962/4885POLB 30/4885
US-11877999-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI SMN1; SMN2 4022/4885HPGD 962/4885POLB 30/4885
US-20220142973-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI SMN1; SMN2 4022/4885HPGD 962/4885POLB 30/4885
US-12533339-B2 Small molecule antiviral drug treatment for human papillomavirus infections CCND3, CCND1, TPD52L2 SMN1; SMN2 2804/4885HPGD 2488/4885POLB 424/4885
US-20240173291-A1 SMALL MOLECULE ANTIVIRAL DRUG TREATMENT FOR HUMAN PAPILLOMAVIRUS INFECTIONS TP53, EIF2AK2, POLI SMN1; SMN2 4022/4885HPGD 962/4885POLB 30/4885
US-20100249088-A1 AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF TRPV1, FGFR3, GPR17 SMN1; SMN2 3213/4885HPGD 1224/4885POLB 4348/4885
US-11628158-B2 Small molecule antiviral drug treatment for human papillomavirus infections TP53, EIF2AK2, POLI SMN1; SMN2 4022/4885HPGD 962/4885POLB 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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