Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4626781 | 0.88 | HTT (0.68) | MAPTLMNANPC1RAB9AKMT2A | |
| SCHEMBL10889755 | 0.87 | KMT2A (0.69) | MAPTLMNAKMT2AAPEX1ALDH1A1 | |
| SCHEMBL16352053 | 0.86 | RAB9A (0.62) | MAPTLMNANPC1RAB9AHPGD | |
| SCHEMBL3796253 | 0.86 | RAB9A (0.62) | MAPTLMNANPC1RAB9AHPGD | |
| SCHEMBL822668 | 0.86 | RAB9A (0.62) | MAPTLMNANPC1RAB9AHPGD | |
| SCHEMBL27592472 | 0.86 | NPC1 (0.67) | MAPTLMNANPC1RAB9AHPGD | |
| SCHEMBL10674129 | 0.85 | USP2 (0.75) | MAPTLMNANPC1RAB9AKMT2A | |
| SCHEMBL1698253 | 0.84 | LMNA (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL129968 | 0.84 | NPC1 (0.82) | MAPTLMNANPC1RAB9AKMT2A | |
| SCHEMBL1974245 | 0.83 | NLRP3 (0.80) | MAPTLMNANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| WO-2019048923-A2 | TRANS-ISOMERIC HETEROCYCLIC COMPOUNDS AND PREPARATION THEREOF | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2019-03-14 | — | — | WO | claimed |
| EP-2324009-A1 | PROCESS FOR PREPARING CERTAIN CINNAMIDE COMPOUNDS | Eisai R&D Management Co., Ltd. (JP) | 2011-05-25 | — | — | EP | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| WO-2010025197-A1 | PROCESS FOR PREPARING CERTAIN CINNAMIDE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-04 | — | — | WO | claimed |
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-4073242-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | Kumquat Biosciences Inc. (US) | 2022-10-19 | — | — | EP | disclosed |
| CN-115103907-A | Compositions and methods for enhancing immune activity | 金橘生物科技公司 | 2022-09-23 | — | — | CN | disclosed |
| WO-2021119554-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | KUMQUAT BIOSCIENCES INC. (US) | 2021-06-17 | — | — | WO | disclosed |
| WO-2019048923-A2 | TRANS-ISOMERIC HETEROCYCLIC COMPOUNDS AND PREPARATION THEREOF | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2019-03-14 | — | — | WO | disclosed |
| EP-3189039-A1 | NOVEL CRYSTALLINE FORMS OF A BACE INHIBITOR, COMPOSITIONS, AND THEIR USE | Merck Sharp & Dohme Corp. (US) | 2017-07-12 | — | — | EP | disclosed |
| WO-2008151179-A2 | SUBSTITUTED PHENETHYLAMINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-12-11 | — | — | WO | disclosed |
| EP-1435948-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003013517-A1 | AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2003-02-20 | — | — | WO | disclosed |
| EP-0043187-B1 | PESTICIDAL CYCLOBUTYL CARBOXYLIC ESTER COMPRISING COMPOSITIONS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1986-05-14 | — | — | EP | disclosed |
| US-4540710-A | Insecticidal ester enantiomers | THE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1985-09-10 | — | — | US | disclosed |
| US-4391820-A | Insecticidal ester enantiomers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1983-07-05 | — | — | US | disclosed |
| EP-0043187-A1 | Pesticidal cyclobutyl carboxylic ester comprising compositions | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1982-01-06 | — | — | EP | disclosed |