Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | ESRRG | P62508 | 2/20 | 0.56 |
| ▸ | ESRRB | O95718 | 1/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162412 | 0.85 | SMN1; SMN2 (0.82) | HPGDSMN1; SMN2ALDH1A1POLBALOX12 | |
| SCHEMBL11684013 | 0.83 | DNMT3A (0.65) | HPGDSMN1; SMN2MT-CO2ALDH1A1SLC6A5 | |
| SCHEMBL14818759 | 0.80 | MAPK1 (0.74) | HPGDSMN1; SMN2ALDH1A1POLBALOX12 | |
| SCHEMBL11711200 | 0.80 | RAB9A (0.66) | SMN1; SMN2MT-CO2ESRRGESRRBMEN1 | |
| SCHEMBL28574459 | 0.78 | ALDH1A1 (0.73) | HPGDSMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL15400503 | 0.78 | NPC1 (0.66) | HPGDSMN1; SMN2ALDH1A1POLBALOX12 | |
| SCHEMBL23832296 | 0.78 | HPGD (0.58) | HPGDSMN1; SMN2ALDH1A1POLBALOX12 | |
| SCHEMBL11710415 | 0.77 | NPC1 (0.68) | SMN1; SMN2ALDH1A1ESRRGESRRBKDM4E | |
| SCHEMBL11711213 | 0.77 | HPGD (0.60) | HPGDSMN1; SMN2MT-CO2ALDH1A1SLC6A5 | |
| SCHEMBL11711918 | 0.77 | KDM4E (0.50) | HPGDSMN1; SMN2ALDH1A1POLBALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |