SCHEMBL1316489

SCHEMBL1316489

[CH]1C=Cc2cccc3cccc1c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
TSHR P16473 4/20 0.41
HPGD P15428 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41
CES2 O00748 1/20 0.37
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37
MCL1 Q07820 1/20 0.37
MAPK1 P28482 3/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TYMS P04818 1/20 0.34
THRB P10828 1/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30220270 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL30439933 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL26037 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL29575794 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL8872842 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL3099744 0.81 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL23300518 0.78 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL10699512 0.78 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2
SCHEMBL11766347 0.78 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2
Bromide SCHEMBL8065175 0.78 ALDH1A1 (0.50) ALDH1A1HSD17B10TSHRHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111587403-B Composition for hard mask 东友精细化工有限公司 2023-09-19 CN claimed
CN-111587403-A Composition for hard mask 东友精细化工有限公司 2020-08-25 CN claimed
US-20110267574-A1 LIQUID CRYSTAL DISPLAY DEVICE AND COMPOSITION FOR FORMING LIQUID CRYSTAL LAYER SHARP KABUSHIKI KAISHA (JP) 2011-11-03 US claimed
EP-1155001-A4 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2003-05-28 EP claimed
EP-0861210-B1 USE OF SULFONAMIDES FOR CONTROLLING BIOFOULING BUCKMAN LABOR INC (US) 2001-12-12 EP claimed
EP-1155001-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2001-11-21 EP claimed
WO-2000050406-A1 ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES LION BIOSCIENCE AG (DE) 2000-08-31 WO claimed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US claimed
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 CN disclosed
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-11-07 US disclosed
CN-111587403-B Composition for hard mask 东友精细化工有限公司 2023-09-19 CN disclosed
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 CN disclosed
US-11653565-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-05-16 US disclosed
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-04-25 US disclosed
CN-1107066-C Diaza-spiro [3,5] nonane derivatives HOFFMANN LA ROCHE (CH) 2003-04-30 CN disclosed
CN-1242366-A Diaza-spiro [3,5] nonane derivatives HOFFMANN LA ROCHE (CH) 2000-01-26 CN disclosed
CN-1242367-A Spiro [Piperidine-4,1'-pyrrolo[3,4-c] pyrrole] HOFFMANN LA ROCHE (CH) 2000-01-26 CN disclosed
US-5516577-A Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1996-05-14 US disclosed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US disclosed
EP-0569827-A2 Organic electroluminescence device IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807656-B2 Polycyclic aromatic compound and light emission layer-forming composition ARNT, TYR, NLRP3 ALDH1A1 2119/4885HSD17B10 4513/4885TSHR 4586/4885
US-11653565-B2 Polycyclic aromatic compound ETV6, EBPL, EML4 ALDH1A1 3566/4885HSD17B10 4517/4885TSHR 4531/4885
US-11637250-B2 Polycyclic aromatic compound and light emitting layer-forming composition C9, TYR, CCNA1 ALDH1A1 990/4885HSD17B10 3137/4885TSHR 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.