Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016934 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL13166304 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL13166302 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL8921740 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL1148684 | 1.00 | — | — | |
| SCHEMBL1485899 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL3036481 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL8918 | 1.00 | — | — | |
| SCHEMBL3035987 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL13166301 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239629-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE CDK2 | Plexium, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023061457-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 百奥泰生物制药股份有限公司 | 2023-04-20 | — | — | WO | disclosed |
| US-20230018702-A1 | QUINAZOLINONES AS PARP14 INHIBITORS | ABBVIE BIOTECHNOLOGY LTD (BM) | 2023-01-19 | — | — | US | disclosed |
| US-20220389026-A1 | TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-12-08 | — | — | US | disclosed |
| WO-2022140246-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | HANGZHOU JIJING PHARMACEUTICAL TECHNOLOGY LIMITED (CN) | 2022-06-30 | — | — | WO | disclosed |
| US-11358950-B2 | SMAC mimetics used as IAP inhibitors and use thereof | CHIA TAI TIANGQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-06-14 | — | — | US | disclosed |
| US-20220119368-A1 | FLUOROVINYLBENZAMIDE COMPOUND AS PD-L1 IMMUNOMODULATOR | ShanghaiFosunPharmaceuticalIndustrialDevelopmentCo.,Ltd (CN) | 2022-04-21 | — | — | US | disclosed |
| US-20210380599-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2021-12-09 | — | — | US | disclosed |
| US-20210371400-A1 | SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-12-02 | — | — | US | disclosed |
| US-20210340141-A1 | TLR8 AGONIST | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2021-11-04 | — | — | US | disclosed |
| US-9938577-B2 | Conjugated polymeric particle and method of making same | Life Technologies Corporation (US) | 2018-04-10 | — | — | US | disclosed |
| EP-3091011-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2017-12-27 | — | — | EP | disclosed |
| EP-2939842-B1 | IMAGE PROCESSING METHOD AND IMAGE PROCESSING APPARATUS | CANON KK (JP) | 2017-09-06 | — | — | EP | disclosed |
| EP-2938595-B1 | METHOD FOR THE SYNTHESIS OF A HYDRAZINE THAT CAN BE USED IN THE TREATMENT OF THE PAPILLOMA VIRUS | ANACONDA PHARMA (FR) | 2017-06-14 | — | — | EP | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-7803804-B2 | Substituted pyrazines for use in the treatment of inflammatory or allergic conditions | NOVARTIS AG (CH) | 2010-09-28 | — | — | US | disclosed |
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-07-30 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-20080312217-A1 | Organic Compounds | NOVARTIS AG | 2008-12-18 | — | — | US | disclosed |
| US-7262185-B2 | Benzazepine derivative, process for producing the same, and use | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371400-A1 | SMAC MIMETICS USED AS IAP INHIBITORS AND USE THEREOF | BIRC7, BIRC5, BIRC2 | ALDH1A1 3894/4885HSD17B10 3742/4885SIGMAR1 4573/4885 |
| US-20220119368-A1 | FLUOROVINYLBENZAMIDE COMPOUND AS PD-L1 IMMUNOMODULATOR | CD274, PDCD1LG2, PDCD1 | ALDH1A1 65/4885HSD17B10 2854/4885SIGMAR1 4328/4885 |
| US-20210380599-A1 | QUINOLINO-PYRROLIDIN-2-ONE DERIVATIVE AND APPLICATION THEREOF | ATM, CHEK2, CHEK1 | ALDH1A1 2781/4885HSD17B10 3539/4885SIGMAR1 4819/4885 |
| US-20230018702-A1 | QUINAZOLINONES AS PARP14 INHIBITORS | PARP14, PARP15, PARP11 | ALDH1A1 2388/4885HSD17B10 2258/4885SIGMAR1 4526/4885 |
| US-20220389026-A1 | TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR | CDC7, CDC5L, CDC16 | ALDH1A1 3977/4885HSD17B10 1637/4885SIGMAR1 4037/4885 |
| US-20090191193-A1 | Aryl Vinyl Sulfides, Sulfones, Sulfoxides and Sulfonamides, Derivatives Thereof and Therapeutic Uses Thereof | ARSA, STS, SULT2A1 | ALDH1A1 249/4885HSD17B10 2278/4885SIGMAR1 2742/4885 |
| US-11358950-B2 | SMAC mimetics used as IAP inhibitors and use thereof | BIRC7, BIRC5, BIRC2 | ALDH1A1 3894/4885HSD17B10 3742/4885SIGMAR1 4573/4885 |
| US-20210340141-A1 | TLR8 AGONIST | TLR8, TLR7, TLR1 | ALDH1A1 3196/4885HSD17B10 2935/4885SIGMAR1 289/4885 |
| US-20080312217-A1 | Organic Compounds | TRPA1, TRPV1, CHRM1 | ALDH1A1 567/4885HSD17B10 3142/4885SIGMAR1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.