Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8819203 | 0.78 | TSHR (0.71) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL8717561 | 0.77 | HRH3 (0.53) | TSHRLMNANPSR1TP53KDM4E | |
| SCHEMBL8819880 | 0.77 | TSHR (0.69) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL15127558 | 0.76 | TSHR (0.65) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL8820471 | 0.71 | TSHR (0.71) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL3633383 | 0.70 | TSHR (0.61) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL10722429 | 0.70 | MEN1 (0.70) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL8719963 | 0.69 | OPRK1 (0.55) | NPSR1ALDH1A1MAPK1ATMCCR1 | |
| SCHEMBL27401731 | 0.69 | OPRK1 (0.55) | NPSR1ALDH1A1MAPK1ATMCCR1 | |
| SCHEMBL1102309 | 0.69 | HPGD (0.84) | MEN1KMT2ATSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | ZACHARON PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100248365-A1 | GANGLIOSIDE BIOSYNTHESIS MODULATORS | UGCG, MAGT1, STT3B | MEN1 1262/4885KMT2A 1738/4885TSHR 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.