Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168799 | 0.92 | ALDH1A1 (0.45) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2809218 | 0.87 | REN (0.44) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2809236 | 0.86 | REN (0.43) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2807782 | 0.78 | REN (0.50) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2805180 | 0.73 | REN (0.48) | ALDH1A1POLBKMT2AHPGDCYP3A4 | |
| SCHEMBL13434188 | 0.72 | MAPT (0.46) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL13434196 | 0.71 | MAPT (0.45) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2812260 | 0.68 | REN (0.48) | POLBKMT2AHPGDCYP3A4CYP2D6 | |
| SCHEMBL8235590 | 0.68 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL90317 | 0.68 | ALDH1A1 (0.44) | ALDH1A1GAAPOLBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240644-A1 | MORPHOLINE DERIVATIVE | REN, AGTR1, AGTR2 | ALDH1A1 2202/4885GAA 2117/4885POLB 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.