Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 15/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 15/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.42 |
| ▸ | ITGAV | P06756 | 10/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14431255 | 0.85 | ITGB1 (0.50) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL3048694 | 0.85 | ITGB1 (0.50) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL13170301 | 0.83 | ITGB1 (0.53) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL6494288 | 0.83 | ITGB3 (0.52) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL13170303 | 0.82 | ITGB1 (0.51) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL5204669 | 0.81 | ITGB1 (0.49) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL5204428 | 0.79 | ITGB1 (0.47) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL6496052 | 0.79 | ITGB1 (0.47) | ITGB1ITGA5MDM4MDM2ITGB3 | |
| SCHEMBL3041592 | 0.79 | ITGB3 (0.53) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL5207016 | 0.78 | ITGB1 (0.42) | ITGB1ITGA5MDM4MDM2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803399-B2 | Delivery system for nucleic acids | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-09-28 | — | — | US | disclosed |