SCHEMBL13170363

SCHEMBL13170363

CC(=O)[C@@H]1CN(C)[C@H](C)C(=O)N1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13435404 1.00 TSHR (0.30) TSHR
SCHEMBL13170323 1.00 TSHR (0.30) TSHR
SCHEMBL12572203 1.00 TSHR (0.30) TSHR
SCHEMBL13170368 0.85 — —
SCHEMBL13170358 0.77 TSHR (0.34) TSHR
SCHEMBL12572123 0.77 TSHR (0.34) TSHR
SCHEMBL12572121 0.75 TSHR (0.53) TSHR
SCHEMBL13435402 0.75 TSHR (0.53) TSHR
SCHEMBL12121674 0.74 ALOX5 (0.34) TSHR
SCHEMBL12121677 0.74 ALOX5 (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7795221-B2 Linear natriuretic peptide constructs PALATIN TECHNOLOGIES, INC. (US) 2010-09-14 — — US disclosed
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2010-03-25 — — US disclosed
US-20070232546-A1 Linear Natriuretic Peptide Constructs PALATIN TECHNOLOGIES, INC. (US) 2007-10-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070232546-A1 Linear Natriuretic Peptide Constructs NPR1, NPR3, NPPA TSHR 40/4885
US-20100075895-A1 Cyclic Natriuretic Peptide Constructs NPR1, NPR3, NPPA TSHR 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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