Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13170491 | 0.82 | PDE4B (0.52) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL13170578 | 0.82 | PDE4B (0.52) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL20160837 | 0.82 | PDE4B (0.52) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL4250744 | 0.82 | PDE4B (0.52) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL14094715 | 0.82 | FFAR1 (0.47) | LMNAPDE4BHTTABCC4GAA | |
| SCHEMBL20160807 | 0.80 | LMNA (0.52) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL2914914 | 0.80 | TP53 (0.68) | TP53ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL403303 | 0.80 | TP53 (0.68) | TP53ALDH1A1MAPTLMNANPC1 | |
| SCHEMBL516326 | 0.80 | PDE4B (0.54) | ALDH1A1MAPTLMNANPC1MAPK1 | |
| SCHEMBL13191568 | 0.79 | PDE4B (0.48) | EGFRALDH1A1MAPTPDE4BPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222432-A1 | Synthetic Carbon Nanotubes | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222432-A1 | Synthetic Carbon Nanotubes | CYCS, CHN2, TUBA3C | EGFR 1621/4885TP53 1034/4885ALDH1A1 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.