Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Abietic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.80 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 3/20 | 0.80 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.80 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.80 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.80 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.80 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abietic Acid SCHEMBL1317077 | 1.00 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL8335225 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL30176404 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL8335223 | 0.99 | HSD17B10 (0.81) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL600776 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL5711211 | 0.98 | PDK1 (0.83) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL10524200 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL16401716 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL2373053 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 | |
| Abietic Acid SCHEMBL600775 | 0.98 | HSD17B10 (0.80) | HSD17B10ALOX15LMNAPDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025051850-A1 | ANTIFOULING COATING SYSTEM | JOTUN A/S (NO) | 2025-03-13 | — | — | WO | claimed |
| CN-118006255-B | Method for preparing adhesive from modified melamine formaldehyde resin | 江苏国立化工科技有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118145915-B | High heat insulation calcium silicate board | 山东君鹏节能科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118145915-A | High heat insulation calcium silicate board | 山东君鹏节能科技有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117801525-B | High-performance composite heat stabilizer and preparation method thereof | 东莞市振中塑胶有限公司 | 2024-06-04 | — | — | CN | claimed |
| CN-118006255-A | Method for preparing adhesive from modified melamine formaldehyde resin | 江苏国立化工科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117899635-A | Natural aromatic formaldehyde-removing spray and preparation method and application thereof | 福建千祥环保科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117801525-A | High-performance composite heat stabilizer and preparation method thereof | 东莞市振中塑胶有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117378622-A | Compound mite-killing smoke agent for cultivating auricularia auricula and application thereof | 江苏省农业科学院 | 2024-01-12 | — | — | CN | claimed |
| CN-113387661-B | Concrete and preparation method thereof | 西安天盛混凝土有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114593431-A | System and method for enhancing atomization effect of oily wastewater by using microwaves | 山东环沃环保科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-113930206-A | High-temperature-resistant adhesive and preparation method and application thereof | 东莞市扬涛包装材料有限公司 | 2022-01-14 | — | — | CN | claimed |
| CN-111205025-B | Waterproof mortar | 深圳市奇信集团股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-113387661-A | Concrete and preparation method thereof | 西安天盛混凝土有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-108047516-B | Preparation method of rubber damping pad | 台州宝诚科技服务有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111205025-A | Waterproof mortar | 深圳市奇信集团股份有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-107361449-B | Shark leather shoe | 浙江工贸职业技术学院 | 2020-05-08 | — | — | CN | claimed |
| US-5378279-A | Enhanced cement mixed with selected aggregates | CONROY MICHEL (FR) | 1995-01-03 | — | — | US | claimed |
| WO-2026089950-A1 | ARTICLES CONTAINING COMPOSTABLE HOT MELT ADHESIVES | HENKEL AG & CO. KGAA (DE) | 2026-04-30 | — | — | WO | disclosed |
| US-3989657-A | Stabilization of polybutadiene resin with metal salt | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-11-02 | — | — | US | disclosed |