SCHEMBL1317201

SCHEMBL1317201

Cc1ccccc1-c1ccc(C(=O)O)c(NC(=O)c2cncc(-c3ccccc3)c2)c1.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACLY P53396 3/20 0.51
CCNC P24863 1/20 0.49
CDK8 P49336 1/20 0.49
NR1H4 Q96RI1 1/20 0.49
CHRNA7 P36544 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CAMKK2 Q96RR4 1/20 0.47
CTSA P10619 1/20 0.47
DHODH Q02127 1/20 0.46
MCL1 Q07820 1/20 0.45
SCN10A Q9Y5Y9 3/20 0.45
SCN2A Q99250 1/20 0.45
XDH P47989 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
KDM6B O15054 2/20 0.44
KDM4C Q9H3R0 2/20 0.44
SUCNR1 Q9BXA5 1/20 0.44
HDAC1 Q13547 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12118092 0.99 ACLY (0.52) ACLYCCNCCDK8NR1H4CHRNA7
SCHEMBL1317198 0.90 CCNC (0.48) ACLYCCNCCDK8NR1H4CHRNA7
SCHEMBL12118107 0.90 MAPK1 (0.52) CCNCCDK8NR1H4CHRNA7ALDH1A1
SCHEMBL1316095 0.88 ACLY (0.52) ACLYALDH1A1DHODHXDHKDM4C
SCHEMBL1315751 0.88 ACLY (0.64) ACLYALDH1A1DHODHXDHKDM4C
SCHEMBL1317189 0.87 ACLY (0.51) ACLYCCNCCDK8ALDH1A1CTSA
SCHEMBL1316819 0.87 ACLY (0.51) ACLYCCNCCDK8ALDH1A1CAMKK2
SCHEMBL12118197 0.87 ACLY (0.53) ACLYALDH1A1DHODHXDHKDM4C
SCHEMBL12118131 0.87 ACLY (0.58) ACLYCCNCCDK8CHRNA7ALDH1A1
SCHEMBL12118094 0.86 CCNC (0.45) ACLYCCNCCDK8NR1H4CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 ACLY 295/4885CCNC 3376/4885CDK8 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.