Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL9716572 | 1.00 | NOS1 (0.32) | NOS1ALDH1A1CYP3A4MAPTCYP2D6 | |
| Guanidine SCHEMBL7198349 | 0.91 | NOS1 (0.36) | NOS1ALDH1A1CYP3A4MAPTCYP2D6 | |
| Boric Acid SCHEMBL5691804 | 0.85 | LMNA (0.31) | ALDH1A1CYP3A4 | |
| Boric Acid SCHEMBL25195294 | 0.85 | LMNA (0.31) | ALDH1A1CYP3A4 | |
| Boric Acid SCHEMBL8851917 | 0.85 | LMNA (0.31) | ALDH1A1CYP3A4 | |
| Boric Acid SCHEMBL28257526 | 0.82 | MEN1 (0.30) | ALDH1A1CYP3A4 | |
| Boric Acid SCHEMBL28444334 | 0.79 | ALDH1A1 (0.40) | ALDH1A1 | |
| Acetic Acid SCHEMBL28252197 | 0.79 | FFAR3 (0.35) | — | |
| Guanidine SCHEMBL1317562 | 0.77 | NUDT1 (0.30) | — | |
| Guanidine SCHEMBL1318808 | 0.77 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146727-B1 | FLAME RETARDED POLYESTER BLEND | BASF SE (DE) | 2024-07-10 | — | — | EP | disclosed |
| US-20240209184-A1 | ALIPHATIC COPOLYAMIDE COMPOSITION | BASF SE (DE) | 2024-06-27 | — | — | US | disclosed |
| EP-4127062-B1 | HEAT-AGING RESISTANT POLYAMIDE MOLDING COMPOSITIONS | BASF SE (DE) | 2024-05-08 | — | — | EP | disclosed |
| EP-4121483-B1 | PLASTICIZED POLYAMIDE MOLDING COMPOSITIONS | BASF SE (DE) | 2024-05-08 | — | — | EP | disclosed |
| EP-4110869-B1 | HEAT-AGING RESISTANT POLYAMIDE MOLDING COMPOSITIONS | BASF SE (DE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2024068508-A1 | THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-3 | BASF SE (DE) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024068510-A1 | THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-2 | BASF SE (DE) | 2024-04-04 | — | — | WO | disclosed |
| WO-2024068509-A1 | THERMOPLASTIC MOULDING COMPOSITIONS HAVING AN IMPROVED COLOUR STABILITY-1 | BASF SE (DE) | 2024-04-04 | — | — | WO | disclosed |
| EP-4330021-A1 | ALIPHATIC COPOLYAMIDE COMPOSITION | BASF SE (DE) | 2024-03-06 | — | — | EP | disclosed |
| WO-2023237603-A1 | RECYCLING METHOD FOR PRODUCING A POLYAMIDE COMPOUND | BASF SE (DE) | 2023-12-14 | — | — | WO | disclosed |
| EP-2389412-A1 | FLAME RETARDED THERMOPLASTIC COMPOSITION, PROCESS FOR MAKING SAME AND ARTICLE CONTAINING SAME | Icl-ip America Inc. (US) | 2011-11-30 | — | — | EP | disclosed |
| US-20110274932-A1 | COMPONENT COMPRISING AN INSERT PART AND PLASTICS JACKETING, AND PROCESS FOR PRODUCTION OF THE COMPONENT | BASF SE (DE) | 2011-11-10 | — | — | US | disclosed |
| US-20110257323-A1 | ECO-FRIENDLY POLYPROPYLENE-POLYLACTIC ACID COMPOSITE COMPOSITION | HYUNDAI MOTOR COMPANY (KR) | 2011-10-20 | — | — | US | disclosed |
| CN-101035865-B | Flowable thermoplastic materials with halogen-free flame protection | BASF AG | 2011-09-28 | — | — | CN | disclosed |
| WO-2010085404-A1 | FLAME RETARDED THERMOPLASTIC COMPOSITION, PROCESS FOR MAKING SAME AND ARTICLE CONTAINING SAME | ICL-IP AMERICA INC. (US) | 2010-07-29 | — | — | WO | disclosed |
| US-20090048373-A1 | Laser-markable flameproof molding compounds and laser-markable and laser-marked products obtained from said molding compounds | TICONA GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
| US-20080194741-A1 | Flowable Thermoplastic Materials With Halogen-Free Flame Protection | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-14 | — | — | US | disclosed |
| US-20080161490-A1 | Halogen-Free Flame-Retardant Thermoplastic Moulding Compositions Based on Polyamide With Increased Glow-Wire Resistance | LANXESS Performance Materials GmbH (DE) | 2008-07-03 | — | — | US | disclosed |
| CN-101035865-A | Flowable thermoplastic materials with halogen-free flame protection | BASF AG (DE) | 2007-09-12 | — | — | CN | disclosed |
| US-7169838-B2 | Halogen-free flameproof polyester | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-30 | — | — | US | disclosed |