SCHEMBL1317872

SCHEMBL1317872

O=C(O)c1ccc(-n2cccn2)cc1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.48
PPARA Q07869 2/20 0.48
MCL1 Q07820 3/20 0.47
LMNA P02545 1/20 0.47
FOLH1 Q04609 1/20 0.45
NOTUM Q6P988 1/20 0.43
KAT6A Q92794 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PTGER1 P34995 1/20 0.41
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1315579 0.90 FOLH1 (0.54) PPARGPPARALMNAFOLH1KAT6A
SCHEMBL1317623 0.89 NOTUM (0.53) PPARGPPARALMNANOTUMKAT6A
SCHEMBL12121579 0.83 TP53 (0.44) LMNA
SCHEMBL15056311 0.81 KAT6A (0.45) LMNANOTUMKAT6APTGER1
SCHEMBL5064726 0.81 ALDH1A1 (0.48) LMNANOTUMKAT6AKDM4EALDH1A1
SCHEMBL5759590 0.80 ALDH1A1 (0.47) LMNAKDM4EALDH1A1L3MBTL1
SCHEMBL27989369 0.80 HRH3 (0.48) MCL1FOLH1PTGER1
SCHEMBL27828454 0.80 HTT (0.56) MCL1LMNAFOLH1KDM4E
Hydrochloric Acid SCHEMBL1316721 0.79 HRH3 (0.47) MCL1FOLH1PTGER1
SCHEMBL27758845 0.78 LMNA (0.44) LMNANOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102333757-B N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2014-11-26 CN disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
CN-102333757-A N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2012-01-25 CN disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 PPARG 1380/4885PPARA 576/4885MCL1 3649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.