Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.51 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12121924 | 0.90 | MMP9 (0.64) | HPGDSMMP9NPC1PDE2AMEN1 | |
| SCHEMBL1320071 | 0.87 | MMP9 (0.58) | HPGDSMMP9NPC1PDE2ARAB9A | |
| SCHEMBL23839968 | 0.86 | MEN1 (0.59) | HPGDSMMP9NPC1PDE2ARAB9A | |
| SCHEMBL1320867 | 0.86 | MEN1 (0.59) | HPGDSMMP9NPC1PDE2ARAB9A | |
| SCHEMBL1320543 | 0.86 | MEN1 (0.64) | HPGDSMMP9NPC1RAB9AMEN1 | |
| SCHEMBL29375958 | 0.85 | MMP9 (0.56) | HPGDSMMP9NPC1PDE2AMEN1 | |
| SCHEMBL1643774 | 0.83 | TP53 (0.55) | HPGDSMMP9NPC1PDE2ARAB9A | |
| SCHEMBL3102386 | 0.83 | ROCK2 (0.72) | HPGDSMMP9UTS2RROCK2ROCK1 | |
| SCHEMBL30530125 | 0.82 | LMNA (0.55) | HPGDSNPC1RAB9AMEN1KMT2A | |
| SCHEMBL2405077 | 0.82 | MMP9 (0.58) | MMP9NPC1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269834-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-11-03 | — | — | US | disclosed |
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269834-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | SARS1, ACE2, ACE | HPGDS 515/4885MMP9 974/4885NPC1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.