Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23839968 | 1.00 | MEN1 (0.59) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL12121924 | 0.87 | MMP9 (0.64) | MEN1KMT2ANPC1MMP9HPGDS | |
| SCHEMBL1318145 | 0.86 | HPGDS (0.60) | MEN1KMT2ANPC1RAB9AMMP9 | |
| SCHEMBL1319215 | 0.84 | GPR139 (0.65) | MEN1KMT2ANPC1RAB9AMMP9 | |
| SCHEMBL29793739 | 0.81 | ALDH1A1 (0.62) | MEN1KMT2ANPC1GPR139ATM | |
| SCHEMBL1643774 | 0.81 | TP53 (0.55) | MEN1KMT2ANPC1RAB9AMMP9 | |
| SCHEMBL1318551 | 0.81 | MMP9 (0.59) | MEN1KMT2AMMP9HPGDSPDE2A | |
| SCHEMBL2409358 | 0.80 | HDAC8 (0.67) | MEN1KMT2ANPC1GPR139ATM | |
| SCHEMBL1320071 | 0.80 | MMP9 (0.58) | MEN1KMT2ANPC1RAB9AMMP9 | |
| SCHEMBL30544977 | 0.79 | MMP9 (0.69) | MEN1KMT2AMMP9HPGDSPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269834-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-11-03 | — | — | US | disclosed |
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269834-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | SARS1, ACE2, ACE | MEN1 4233/4885KMT2A 3537/4885NPC1 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.