SCHEMBL1318263

SCHEMBL1318263

CCCOc1ccc(O)c(C(=O)OC)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
PLA2G2A P14555 1/20 0.48
MAPT P10636 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
PTGS2 P35354 1/20 0.47
PLK1 P53350 1/20 0.46
MCL1 Q07820 1/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.45
EGFR P00533 2/20 0.45
NOX4 Q9NPH5 1/20 0.45
SLC5A1 P13866 1/20 0.44
SLC5A2 P31639 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12587312 0.94 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL9402555 0.90 MAOA (0.59) CA12CA1CA2CA7CA9
SCHEMBL4654884 0.90 MAOA (0.59) CA12CA1CA2CA7CA9
SCHEMBL9698412 0.90 MAOA (0.59) CA12CA1CA2CA7CA9
SCHEMBL9324741 0.90 MAOA (0.59) CA12CA1CA2CA7CA9
SCHEMBL4566999 0.88 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL18199320 0.87 PLA2G2A (0.50) PLA2G2AMAPTMAOAMAOBPLK1
SCHEMBL12036040 0.87 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL5505003 0.86 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL27139421 0.84 PLA2G2A (0.48) PLA2G2AMAPTMAOAMAOBPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102333757-B N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2014-11-26 CN disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
CN-102333757-A N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2012-01-25 CN disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 CA12 1033/4885CA1 773/4885CA2 311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.