Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183431 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL30486520 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL14841042 | 0.86 | DPP4 (0.47) | ALDH1A1SMN1; SMN2HTR2AMEN1KMT2A | |
| SCHEMBL5239394 | 0.85 | ALDH1A1 (0.63) | ALDH1A1TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL27967297 | 0.84 | HTR2A (0.48) | ALDH1A1TDP1KDM4ESMN1; SMN2HTR2A | |
| SCHEMBL19030269 | 0.83 | HTR2A (0.47) | ALDH1A1KDM4ESMN1; SMN2HTR2AMEN1 | |
| SCHEMBL5234910 | 0.82 | OPRD1 (0.50) | ALDH1A1MAPTLMNAL3MBTL1KDM4E | |
| SCHEMBL5241508 | 0.81 | LMNA (0.57) | ALDH1A1TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL29935055 | 0.79 | HDAC2 (0.44) | ALDH1A1SMN1; SMN2HTR2AMEN1KMT2A | |
| SCHEMBL19030579 | 0.79 | HDAC2 (0.44) | ALDH1A1SMN1; SMN2HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110400-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-09-30 | — | — | WO | disclosed |