SCHEMBL5239394

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13183440	0.93	ALDH1A1 (0.57)	ALDH1A1KDM4EPOLBALOX15TDP1
	SCHEMBL8116325	0.85	GPR119 (0.51)	ALDH1A1KDM4EPOLBALOX15KMT2A
	SCHEMBL13183441	0.85	ALDH1A1 (0.61)	ALDH1A1KDM4EPOLBALOX15TDP1
	SCHEMBL4826185	0.85	ALDH1A1 (0.63)	ALDH1A1KDM4EPOLBALOX15TDP1
	SCHEMBL17848532	0.82	RIPK1 (0.46)	ALDH1A1KDM4EPOLBKMT2AMEN1
	SCHEMBL376254	0.80	ALDH1A1 (0.45)	ALDH1A1KDM4EPOLBTDP1KMT2A
	SCHEMBL11255386	0.79	RIPK1 (0.61)	ALDH1A1KDM4EALOX15KMT2AMEN1
	SCHEMBL5234910	0.79	OPRD1 (0.50)	ALDH1A1KDM4EKMT2AGAAMEN1
	SCHEMBL5238677	0.79	ALDH1A1 (0.49)	ALDH1A1KDM4EPOLBNOS3NOS1
	SCHEMBL13183431	0.78	ALDH1A1 (0.56)	ALDH1A1KDM4EPOLBTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.