Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 5/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.67 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.67 |
| ▸ | RELA | Q04206 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | METAP2 | P50579 | 2/20 | 0.55 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CBFB | Q13951 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183633 | 0.84 | RAB9A (0.54) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL3336113 | 0.80 | NPC1 (1.00) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL12082222 | 0.78 | RAB9A (0.69) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL13599850 | 0.78 | NPC1 (0.81) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL20677813 | 0.78 | NPC1 (0.75) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL21087565 | 0.77 | ALDH1A1 (0.57) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL26426691 | 0.76 | ALDH1A1 (0.65) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL13183701 | 0.76 | NPC1 (0.78) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL21976303 | 0.73 | MAPT (0.80) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 | |
| SCHEMBL276208 | 0.73 | NPC1 (0.73) | RAB9AALDH1A1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420686-B2 | Linked diimidazole antivirals | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226882-A1 | LINKED DIIMIDAZOLE ANTIVIRALS | EIF2AK2, ZC3HAV1, MAVS | RAB9A 3434/4885ALDH1A1 241/4885NPC1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.