Fluoride Ion

Fluoride Ion

SCHEMBL131861

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nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HRH3 Q9Y5N1 1/20 0.32
MGLL Q99685 1/20 0.31
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
APEX1 P27695 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30
KMT2A Q03164 1/20 0.30
MCL1 Q07820 1/20 0.30
HKDC1 Q2TB90 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL963997 1.00
Fluoride SCHEMBL3926229 0.95 ALDH1A1 (0.31) ALDH1A1HRH3
Fluoride SCHEMBL633913 0.95
Fluoride SCHEMBL1062136 0.95 ALDH1A1 (0.31) ALDH1A1HRH3
SCHEMBL1334882 0.95
Fluoride Ion SCHEMBL728564 0.90 ALDH1A1 (0.33) ALDH1A1HRH3MGLLCYP2C9HPGD
Bromide SCHEMBL2244871 0.90
Hydrochloric Acid SCHEMBL691818 0.90
Fluoride Ion SCHEMBL2867038 0.90
Fluoride SCHEMBL6229645 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638458-A1 MALT1 INHIBITORS Janssen Pharmaceutica NV (BE) 2025-10-29 EP disclosed
EP-4217346-B1 NEW COMPOUNDS JANSSEN PHARMACEUTICA NV (BE) 2025-07-02 EP disclosed
CN-115260262-B Cytosine azide Process for the preparation of compounds 深圳赛陆医疗科技有限公司 2024-09-27 CN disclosed
WO-2024133859-A1 MALT1 INHIBITORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 WO disclosed
CN-113166184-B Method for preparing cyclic dinucleotides 百时美施贵宝公司 2024-06-18 CN disclosed
CN-112384520-B Method for producing oligonucleotide compound 日本新药株式会社 2024-06-11 CN disclosed
CN-112888699-B Preparation method of nucleotide for sequencing 深圳华大生命科学研究院 2024-05-17 CN disclosed
EP-4368628-A1 METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE Japan Science and Technology Agency (JP) 2024-05-15 EP disclosed
WO-2024096078-A1 FLOW LIQUID SEPARATION DEVICE, FLOW LIQUID SEPARATION SYSTEM, AND PRODUCTION METHOD FOR COMPOUND HAVING PHOSPHATE BOND 日本新薬株式会社 2024-05-10 WO disclosed
EP-4363418-A1 5-OXO-PYRIDO[2,3-D]PYRIDAZIN-6(5H)-YL ACETAMIDES JANSSEN Pharmaceutica NV (BE) 2024-05-08 EP disclosed
US-7534791-B2 Benzo[b]furane and benzo[b]thiophene derivatives H. LUNDBECK A/S (DK) 2009-05-19 US disclosed
CN-101238101-A 2-(1H-indolylsulfanyl)-aryl amine derivatives LUNDBECK & CO AS H (DK) 2008-08-06 CN disclosed
CN-101208324-A Benzo [ b ] furan and benzo [ b ] thiophene derivatives LUNDBECK & CO AS H (DK) 2008-06-25 CN disclosed
EP-1893596-A2 BENZOÝB¨FURANE AND BENZOÝB¨THIOPHENE DERIVATIVES H.Lundbeck A/S (DK) 2008-03-05 EP disclosed
EP-1893575-A2 2-(1H-INDOLYLSULFANYL)-ARYL AMINE DERIVATIVES H.Lundbeck A/S (DK) 2008-03-05 EP disclosed
WO-2007023395-A2 BENZO[B]FURANE AND BENZO[B]THIOPHENE DERIVATIVES H. LUNDBECK A/S (US) 2007-03-01 WO disclosed
WO-2006134499-A2 2-(1H-INDOLYLSULFANYL)-ARYL AMINE DERIVATIVES H. LUNDBECK A/S (DK) 2006-12-21 WO disclosed
US-20060287382-A1 2-(1H-indolylsulfanyl)-aryl amine derivatives H. LUNDBECK A/S (DK) 2006-12-21 US disclosed
US-20060287386-A1 Benzo[b]furane and benzo[b]thiophene derivatives H. LUNDBECK A/S (DK) 2006-12-21 US disclosed
US-20030089306-A1 Method for producing crystal and/or crystal materials containing fluorine SCHOTT GLAS (DE) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060287386-A1 Benzo[b]furane and benzo[b]thiophene derivatives CYP1B1, TBCB, CYP4B1 ALDH1A1 550/4885HRH3 3284/4885MGLL 4854/4885
US-20060287382-A1 2-(1H-indolylsulfanyl)-aryl amine derivatives CYP11B2, CYP1A2, CYP4B1 ALDH1A1 124/4885HRH3 1213/4885MGLL 3932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.