SCHEMBL131867

SCHEMBL131867

[CH2]c1c(F)cccc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648330 0.84
SCHEMBL14657513 0.80
SCHEMBL7532160 0.80
SCHEMBL5000555 0.80
SCHEMBL15659949 0.80
SCHEMBL535470 0.80
SCHEMBL884999 0.76 HSD11B1 (0.38)
SCHEMBL2639148 0.74 BCAT1 (0.39)
SCHEMBL11208388 0.74 GABRA1 (0.44)
SCHEMBL693558 0.74 NFE2L2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2437 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-112004813-B Oxadiazole compounds for controlling phytopathogenic fungi PI工业有限公司 2024-03-29 CN claimed
US-20240002344-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION FIBROGEN, INC. 2024-01-04 US claimed
EP-4273147-A1 SUBSTITUTED SPIROLACTAMS, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2023-11-08 EP claimed
CN-116874457-A Coumarin derivative containing acylhydrazone sulfoxide and synthetic method and application thereof 中国热带农业科学院环境与植物保护研究所 2023-10-13 CN claimed
EP-3547414-B1 LITHIUM ELECTRODE AND LITHIUM SECONDARY BATTERY COMPRISING SAME LG ENERGY SOLUTION LTD (KR) 2023-09-13 EP claimed
EP-4204400-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION Fibrogen, Inc. (US) 2023-07-05 EP claimed
CN-116348450-A Compounds, compositions and methods for histone lysine demethylase inhibition 菲布罗根有限公司 2023-06-27 CN claimed
CN-112961114-B 2-substituted rupestonic acid isoxazolamide derivative and preparation method and application thereof 中国科学院新疆理化技术研究所 2023-06-09 CN claimed
EP-0793674-A1 HUMAN NEUTROPHIL ELASTASE INHIBITORS CORTECH, INC. (US) 1997-09-10 EP claimed
US-5618792-A USEFUL FOR TREATING ACUTE RESPIRATORY DISEASES, AND MYOCARDIAL ISHCEMIA-REPERFUSION INJURY CORTECH, INC. (US) 1997-04-08 US claimed
WO-1996016080-A1 HUMAN NEUTROPHIL ELASTASE INHIBITORS CORTECH, INC. (US) 1996-05-30 WO claimed
US-5378729-A Diamide derivatives RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-01-03 US claimed
WO-1990015069-A2 AMINO ACID DERIVATIVE ANTICONVULSANT RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1990-12-13 WO claimed
EP-0400440-A1 Amino acid derivative anticonvulsant RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1990-12-05 EP claimed
EP-0185381-B1 2-AZOLYLMETHYL-3-DIFLUOROBENZYLOXY-2,3-DIHYDROFLUOROBENZO(B)THIOPHENES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM SCHERING CORPORATION (US) 1989-07-26 EP claimed
US-4316015-A 6H-1,2,4,6-Thiatriazine-1,1-dioxides BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
EP-0021520-A1 (Cycloalkyl)alkoxyimino-substituted cyclopropanecarboxylate esters, process for their manufacture, pesticidal compositions containing them, and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1981-01-07 EP claimed
US-4042369-A HERBICIDES SHELL OIL COMPANY (US) 1977-08-16 US claimed