Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188766 | 0.79 | ABL1 (0.52) | LMNAMAPTMEN1KMT2ACYP2C9 | |
| SCHEMBL3713386 | 0.79 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTMEN1ALDH1A1 | |
| SCHEMBL3714807 | 0.78 | CA12 (0.46) | L3MBTL1KDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL3714227 | 0.78 | TSHR (0.45) | L3MBTL1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL3713780 | 0.78 | TSHR (0.45) | L3MBTL1KDM4EMAPTALDH1A1HTT | |
| SCHEMBL13188764 | 0.76 | POLB (0.50) | L3MBTL1LMNAHTTCYP3A4CYP2D6 | |
| SCHEMBL30925065 | 0.76 | ADORA1 (0.52) | L3MBTL1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL29214320 | 0.76 | ADORA1 (0.52) | L3MBTL1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL3713958 | 0.75 | L3MBTL1 (0.42) | L3MBTL1LMNAKDM4EMAPTMEN1 | |
| SCHEMBL3713408 | 0.72 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |