Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713386 | 0.89 | L3MBTL1 (0.46) | L3MBTL1LMNAAHRPLA2G2AMAPT | |
| SCHEMBL3709574 | 0.87 | ACACB (0.38) | LMNAAHRTP53KMT2AMEN1 | |
| SCHEMBL3710281 | 0.85 | GAA (0.43) | L3MBTL1MAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL3713408 | 0.81 | L3MBTL1 (0.39) | L3MBTL1LMNAP2RY12MAPTKMT2A | |
| SCHEMBL3714487 | 0.79 | KCNH3 (0.40) | L3MBTL1PLA2G2AP2RY12MAPTKMT2A | |
| SCHEMBL3714882 | 0.79 | L3MBTL1 (0.49) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3715411 | 0.77 | CYP19A1 (0.41) | LMNAAHRTP53KMT2AMEN1 | |
| SCHEMBL3709987 | 0.77 | POLB (0.45) | L3MBTL1LMNATP53P2RY12MAPT | |
| SCHEMBL3718011 | 0.75 | FGFR4 (0.40) | L3MBTL1LMNAAHRP2RY12KMT2A | |
| SCHEMBL13187809 | 0.75 | L3MBTL1 (0.47) | L3MBTL1LMNAAHRPLA2G2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |