Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713958 | 0.89 | L3MBTL1 (0.42) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3713408 | 0.85 | L3MBTL1 (0.39) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3714882 | 0.83 | L3MBTL1 (0.49) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3710281 | 0.82 | GAA (0.43) | L3MBTL1MAPTHPGDALDH1A1CYP1A2 | |
| SCHEMBL3715704 | 0.81 | FFAR1 (0.40) | GRM5CYP2C9CYP2C19AHRFFAR1 | |
| SCHEMBL3709987 | 0.80 | POLB (0.45) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL13187809 | 0.79 | L3MBTL1 (0.47) | L3MBTL1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL3711805 | 0.74 | CYP19A1 (0.49) | MAPTALDH1A1GRM5AHRCYP19A1 | |
| SCHEMBL3711329 | 0.74 | CYP19A1 (0.41) | ALDH1A1GRM5CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL3709574 | 0.74 | ACACB (0.38) | LMNAKMT2AMEN1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |