Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709987 | 0.90 | POLB (0.45) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL13188314 | 0.80 | HSD17B10 (0.57) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL3711572 | 0.78 | MAPT (0.47) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL13187809 | 0.76 | L3MBTL1 (0.47) | LMNAHTTL3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL3711476 | 0.76 | MAPT (0.46) | POLBLMNAHTTHSD17B10GPR55 | |
| SCHEMBL3710281 | 0.74 | GAA (0.43) | POLBHSD17B10PIK3CAL3MBTL1CYP3A4 | |
| SCHEMBL3713408 | 0.71 | L3MBTL1 (0.39) | POLBLMNAL3MBTL1P2RY12 | |
| SCHEMBL28161448 | 0.71 | PIK3CA (0.67) | HSD17B10MTORPIK3CACYP3A4CYP2D6 | |
| SCHEMBL30925065 | 0.69 | ADORA1 (0.52) | LMNAHSD17B10L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL29214320 | 0.69 | ADORA1 (0.52) | LMNAHSD17B10L3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |