Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | MOK | Q9UQ07 | 8/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710589 | 0.94 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13187747 | 0.88 | SMN1; SMN2 (0.53) | MOKADORA3SMN1; SMN2LMNANPC1 | |
| SCHEMBL13188892 | 0.88 | HDAC6 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13188494 | 0.86 | HDAC6 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13188396 | 0.85 | DYRK1A (0.57) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13188605 | 0.84 | HDAC6 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13188376 | 0.83 | ACP1 (0.58) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3719071 | 0.82 | MAPK1 (0.49) | MOKSMN1; SMN2 | |
| SCHEMBL13188496 | 0.80 | HDAC1 (0.48) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3720406 | 0.80 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |