Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 13/20 | 0.72 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.71 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.71 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.64 |
| ▸ | FADS1 | O60427 | 3/20 | 0.64 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771745 | 0.88 | FADS1 (0.81) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL4270372 | 0.88 | FADS1 (0.81) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13812641 | 0.86 | P2RX1 (0.61) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13189709 | 0.85 | FADS1 (0.82) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13189703 | 0.84 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL11932152 | 0.83 | P2RX1 (1.00) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13812633 | 0.82 | P2RX1 (0.59) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13812563 | 0.82 | P2RX1 (0.59) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL3860231 | 0.81 | P2RX1 (0.78) | P2RX1P2RX4P2RX7TMPRSS4FADS1 | |
| SCHEMBL13812611 | 0.81 | P2RX1 (0.66) | P2RX1P2RX4P2RX7TMPRSS4FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101648-A1 | GLUTAMATE RECEPTOR MODULATORS AND THERAPEUTIC AGENTS | WOOD RICHARD D (US) | 2010-09-10 | — | — | WO | disclosed |