Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 13/20 | 1.00 |
| ▸ | TMPRSS4 | Q9NRS4 | 8/20 | 0.70 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.70 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | IKBKB | O14920 | 1/20 | 0.60 |
| ▸ | CHUK | O15111 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | MYLK | Q15746 | 1/20 | 0.60 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.60 |
| ▸ | FADS1 | O60427 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406630 | 0.86 | P2RX1 (0.75) | P2RX1P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL24824526 | 0.86 | P2RX1 (0.75) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL14363282 | 0.85 | P2RX1 (0.74) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL4270372 | 0.85 | FADS1 (0.81) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL30771745 | 0.85 | FADS1 (0.81) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL13189706 | 0.84 | P2RX1 (0.72) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL1462221 | 0.83 | P2RX1 (0.71) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL11932152 | 0.82 | P2RX1 (1.00) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL29386800 | 0.82 | TMPRSS4 (1.00) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 | |
| SCHEMBL330629 | 0.82 | TMPRSS4 (1.00) | P2RX1TMPRSS4P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010101648-A1 | GLUTAMATE RECEPTOR MODULATORS AND THERAPEUTIC AGENTS | WOOD RICHARD D (US) | 2010-09-10 | — | — | WO | disclosed |