Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 2/20 | 0.81 |
| ▸ | P2RX1 | P51575 | 11/20 | 0.78 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.72 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.72 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4270372 | 1.00 | FADS1 (0.81) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189706 | 0.88 | P2RX1 (0.72) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189709 | 0.86 | FADS1 (0.82) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL14363185 | 0.85 | FADS1 (0.67) | FADS1P2RX1NPC1RAB9ATP53 | |
| SCHEMBL18290068 | 0.85 | P2RX1 (0.80) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13189703 | 0.85 | P2RX1 (1.00) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL11932152 | 0.84 | P2RX1 (1.00) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL3860231 | 0.82 | P2RX1 (0.78) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812620 | 0.82 | FADS1 (0.65) | FADS1P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL13812611 | 0.82 | P2RX1 (0.66) | FADS1P2RX1P2RX4P2RX7TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | ACE2, ACE, TMPRSS2 | FADS1 466/4885P2RX1 2669/4885P2RX4 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.