Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | TACR2 | P21452 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691855 | 0.99 | DRD2 (0.45) | DRD2DRD3HTR1ATACR2SLC6A4 | |
| SCHEMBL13691859 | 0.92 | OPRK1 (0.43) | DRD2DRD3HTR1ATACR2SLC6A4 | |
| SCHEMBL13188483 | 0.91 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL19474295 | 0.91 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13689546 | 0.91 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13691779 | 0.91 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13691778 | 0.91 | DRD2 (0.44) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL19474294 | 0.90 | DRD2 (0.43) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL19474293 | 0.90 | DRD2 (0.43) | DRD2DRD3HTR1ASLC6A4ADRA1A | |
| SCHEMBL13189114 | 0.89 | PIN1 (0.40) | DRD2DRD3HTR1ASLC6A4CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105823-A1 | 3-AMINOALKYL-1,4-DIAZEPAN-2-ONE MELANOCORTIN-5 RECEPTOR ANTAGONISTS | MIMETICA PTY LTD (AU) | 2009-09-03 | — | — | WO | disclosed |