Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.80 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.80 |
| ▸ | USP13 | Q92995 | 1/20 | 0.80 |
| ▸ | EGFR | P00533 | 11/20 | 0.76 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359604 | 0.89 | USP10 (1.00) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL1068401 | 0.89 | USP10 (1.00) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL9921506 | 0.84 | USP10 (0.80) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL7469214 | 0.82 | USP10 (0.76) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL13170963 | 0.81 | USP10 (0.84) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL9921341 | 0.81 | USP10 (0.84) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL13192093 | 0.81 | EGFR (0.67) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL27923391 | 0.80 | EGFR (0.73) | EGFRERBB2LMNA | |
| SCHEMBL9921511 | 0.79 | USP10 (0.70) | USP10PIK3C3USP13EGFRCNR1 | |
| SCHEMBL13191863 | 0.78 | PDE5A (0.76) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258975-A1 | Potent Small Molecule Inhibitors of Autophagy, and Methods of Use Thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (CN) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258975-A1 | Potent Small Molecule Inhibitors of Autophagy, and Methods of Use Thereof | ATG7, BECN1, SQSTM1 | USP10 1695/4885PIK3C3 186/4885USP13 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.