Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.76 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.76 |
| ▸ | USP13 | Q92995 | 1/20 | 0.76 |
| ▸ | EGFR | P00533 | 8/20 | 0.68 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.68 |
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359604 | 0.87 | USP10 (1.00) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL1068401 | 0.87 | USP10 (1.00) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7468656 | 0.86 | HTT (0.67) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7470174 | 0.83 | HTT (0.57) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL13192098 | 0.82 | EGFR (0.97) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL13191867 | 0.82 | MEN1 (0.73) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL13192047 | 0.82 | USP10 (0.80) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL9921506 | 0.82 | USP10 (0.80) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7470018 | 0.80 | USP10 (0.57) | USP10PIK3C3USP13EGFRERBB2 | |
| SCHEMBL7469278 | 0.79 | PDE5A (0.70) | MEN1KMT2AALDH1A1SMN1; SMN2PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |