Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.72 |
| ▸ | CLK4 | Q9HAZ1 | 12/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.72 |
| ▸ | USP2 | O75604 | 9/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165459 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL31352463 | 0.81 | KDM4E (0.57) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4007243 | 0.79 | CYP1A2 (0.67) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL17165395 | 0.78 | CYP1A2 (0.62) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL8103000 | 0.77 | EGFR (0.65) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL11846266 | 0.76 | CYP1A2 (0.76) | CYP1A2CYP2D6ALDH1A1KDM4EMAPT | |
| SCHEMBL1675080 | 0.76 | CYP1A2 (0.90) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL17593455 | 0.75 | CNR1 (0.75) | — | |
| SCHEMBL4358539 | 0.75 | CYP1A2 (0.65) | CYP1A2CYP3A4CLK4CYP2D6USP2 | |
| SCHEMBL4007548 | 0.75 | MAPK1 (0.63) | CYP1A2CYP3A4CLK4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120258975-A1 | Potent Small Molecule Inhibitors of Autophagy, and Methods of Use Thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY (CN) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258975-A1 | Potent Small Molecule Inhibitors of Autophagy, and Methods of Use Thereof | ATG7, BECN1, SQSTM1 | CYP1A2 4274/4885CYP3A4 4069/4885CLK4 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.