Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | WNT3 | P56703 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MECP2 | P51608 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961007 | 0.92 | ALDH1A1 (0.48) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL13195039 | 0.88 | RECQL (0.47) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL13194934 | 0.82 | PIK3CA (0.46) | MAPTTSHRPIK3CAPRKDC | |
| SCHEMBL13195114 | 0.82 | MTNR1A (0.53) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL13194941 | 0.81 | PIK3CA (0.51) | MEN1KMT2ATP53PIK3CAPRKDC | |
| SCHEMBL13194610 | 0.81 | TNKS (0.46) | TP53PIK3CATNKSTNKS2PRKDC | |
| SCHEMBL13195122 | 0.81 | PIK3CA (0.45) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL13194535 | 0.81 | PIK3CA (0.45) | LMNAMAPTHPGDTSHRHSD17B10 | |
| SCHEMBL11961802 | 0.81 | RECQL (0.46) | HTTLMNAMAPTTSHRHSD17B10 | |
| SCHEMBL13195017 | 0.81 | MTNR1A (0.50) | ALDH1A1HTTMAPTHPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012136492-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |