Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961802 | 0.93 | RECQL (0.46) | RECQLP2RX7PIK3CARAB9APRKDC | |
| SCHEMBL13195022 | 0.88 | ALDH1A1 (0.49) | PIK3CAPRKDCTSHRMAPTSMN1; SMN2 | |
| SCHEMBL11961007 | 0.82 | ALDH1A1 (0.48) | PIK3CAPRKDCTSHRMAPTSMN1; SMN2 | |
| SCHEMBL13194934 | 0.82 | PIK3CA (0.46) | PIK3CAPRKDCKDM4ETSHRNPSR1 | |
| SCHEMBL13195114 | 0.81 | MTNR1A (0.53) | KDM4ETSHRMAPTMTNR1AMTNR1B | |
| SCHEMBL13194941 | 0.81 | PIK3CA (0.51) | PIK3CAPRKDCKDM4EMTNR1AMTNR1B | |
| SCHEMBL13194610 | 0.81 | TNKS (0.46) | PIK3CAPRKDCMTNR1AMTNR1BTP53 | |
| SCHEMBL13195122 | 0.81 | PIK3CA (0.45) | PIK3CAPRKDCTSHRMAPTSMN1; SMN2 | |
| SCHEMBL13194535 | 0.81 | PIK3CA (0.45) | P2RX7PIK3CAPRKDCTSHRMAPT | |
| SCHEMBL13195017 | 0.80 | MTNR1A (0.50) | PIK3CAPRKDCNPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012136492-A1 | WNT PATHWAY ANTAGONISTS | SIENA BIOTECH S.P.A. (IT) | 2012-10-11 | — | — | WO | disclosed |