Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12986530 | 1.00 | SLC6A2 (0.55) | SLC6A2MMP12MMP13 | |
| SCHEMBL12985062 | 0.89 | CYP2E1 (0.42) | SLC6A2MMP12MMP13 | |
| SCHEMBL12986519 | 0.83 | RAB9A (0.41) | — | |
| SCHEMBL12985169 | 0.82 | SLC6A2 (0.46) | SLC6A2MMP12MMP13 | |
| SCHEMBL28808983 | 0.81 | LTB4R (0.39) | SLC6A2MMP12MMP13 | |
| SCHEMBL12984988 | 0.80 | SLC6A2 (0.55) | SLC6A2MMP12MMP13 | |
| SCHEMBL27947836 | 0.79 | PDE10A (0.38) | — | |
| SCHEMBL12986337 | 0.79 | TGFBR1 (0.36) | — | |
| SCHEMBL12984989 | 0.77 | SLC6A2 (0.60) | SLC6A2MMP12MMP13 | |
| SCHEMBL12986239 | 0.77 | SLC6A2 (0.60) | SLC6A2MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809333-B2 | Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | BROWN MATTHEW FRANK (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2012137099-A1 | IMIDAZOLE, PYRAZOLE, AND TRIAZOLE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2012-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140038975-A1 | Imidazole, Pyrazole, and Triazole Derivatives Useful As Antibacterial Agents | AADAC, TPX2, NLRP3 | SLC6A2 4389/4885MMP12 416/4885MMP13 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.