Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 14/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440354 | 0.81 | HTR2A (0.52) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL5443298 | 0.81 | HTR2A (0.52) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| Hydrochloric Acid SCHEMBL5437716 | 0.80 | HTR2A (0.51) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL1009580 | 0.80 | CYP11B1 (0.51) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL6404916 | 0.79 | DRD2 (0.61) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL29228190 | 0.78 | CYP11B2 (0.50) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL24700979 | 0.77 | CYP11B2 (0.64) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL24700865 | 0.77 | CYP11B2 (0.64) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL23363268 | 0.76 | ALDH1A1 (0.54) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL8023501 | 0.76 | CYP11B2 (0.50) | CYP11B1CYP11B2CYP1A2CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334390-B2 | Fungicide N-cycloalkyl-N-bicyclic-carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20100197925-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | Bater SAS (FR) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197925-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | CBR3, CBR1, CYP3A7 | CYP11B1 906/4885CYP11B2 1028/4885CYP1A2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.