Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | KDM1A | O60341 | 4/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442266 | 0.82 | HTR2C (0.65) | MAOAMAOBHRH3HRH1 | |
| SCHEMBL5442260 | 0.82 | HTR2C (0.65) | MAOAMAOBHRH3HRH1 | |
| SCHEMBL5442264 | 0.82 | HTR2C (0.65) | MAOAMAOBHRH3HRH1 | |
| SCHEMBL1843521 | 0.81 | FABP4 (0.53) | MAOAMAOBHRH3CYP2D6KDM1A | |
| SCHEMBL9491587 | 0.81 | TAOK1 (0.53) | MAOAMAOBHRH3CYP2D6KDM1A | |
| SCHEMBL28005936 | 0.81 | MAOA (0.53) | MAOAMAOBHRH3CYP2D6KDM1A | |
| SCHEMBL19978163 | 0.80 | HRH3 (0.48) | MAOAMAOBHRH3KDM1A | |
| SCHEMBL23537862 | 0.80 | HRH3 (0.51) | MAOAMAOBHRH3CYP2D6KDM1A | |
| SCHEMBL30014783 | 0.80 | HRH3 (0.51) | MAOAMAOBHRH3CYP2D6KDM1A | |
| SCHEMBL31318439 | 0.78 | ACHE (0.57) | MAOAMAOBHRH3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185526-B1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | BAYER IP GMBH (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-8334390-B2 | Fungicide N-cycloalkyl-N-bicyclic-carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2012-12-18 | — | — | US | disclosed |
| US-20100197925-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | Bater SAS (FR) | 2010-08-05 | — | — | US | disclosed |
| WO-2009016218-A2 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197925-A1 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIC-CARBOXAMIDE DERIVATIVES | CBR3, CBR1, CYP3A7 | MAOA 354/4885MAOB 1045/4885HRH3 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.