Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 7/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16574247 | 0.89 | LMNA (0.60) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL8373971 | 0.85 | LMNA (0.67) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL19104595 | 0.84 | LMNA (0.65) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL15092710 | 0.83 | LMNA (0.60) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL14999666 | 0.83 | LMNA (0.64) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL10824415 | 0.82 | LMNA (1.00) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL22847567 | 0.81 | LMNA (0.60) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL28409004 | 0.80 | LMNA (0.59) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL13199362 | 0.80 | LMNA (0.63) | LMNACYP1A2KDM4EGRIA1GRIA2 | |
| SCHEMBL12630504 | 0.79 | LMNA (0.59) | LMNACYP1A2KDM4EGRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9702869-B2 | Assays, antibodies, immunogens and compositions related to 5-FU | DEFINED DIAGNOSTICS, LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | PHARMA CINQ, LLC | 2015-03-19 | — | — | US | disclosed |
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | PHARMA CINQ, LLC | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150079612-A1 | Assays, Antibodies, Immunogens and Compositions Related to 5-FU | DPYD, MTHFD1, DHFR | LMNA 4639/4885CYP1A2 2470/4885KDM4E 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.